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1. According the ATS/ERS/JRS/ALAT Research statement, cigarette smoking and which of the following characteristics is associated with development of combined pulmonary fibrosis and emphysema (CPFE)?
2. John is a 71-year-old male with emphysema and suspected smoking-related interstitial fibrosis (SRIF). What finding on a high-resolution computed tomography (HRCT) may confirm SRIF as it is unique to CPFE?
3. The ATS/ERS/JRS/ALAT Research statement recommends consideration of antifibrotic medications at first presentation of which of the following patient types with CPFE?